The present study aims to develop an analysis of how the fast-changing geopolitics and geoeconomics of East Asia impact current and potential trends in cross-regional economic cooperation, with a particular focus on Latin America. The paper revolves around three key trends: i. The Economic Transformation of East Asia; ii. Security and Cooperation in the Pacific; and iii. Mega-Agreements. For each of these areas, the study provides a succinct yet analytical overview of current debates by incorporating both Western and non-Western perspectives from academia and policy.